Deciduous Therapeutics is an early stage, venture-backed biotech company based in San Francisco, California developing novel therapies that activate the endogenous immune biology responsible for treating age-related diseases.
We are looking for a highly ambitious and talented Senior Research Associate / Associate Scientist to join our research team and play a critical role in our research and drug discovery efforts. You will have the opportunity to be an early team member and generate key experimental data in a highly enriching environment. There is significant opportunity to shape your role and advance within the company while learning the ins and outs of both drug development and life as a scientist in a fast-paced start-up. We are a small, hardworking team that is passionate about delivering important medicines that could significantly impact how we age.
Key Responsibilities and Job Functions
- Conduct in vivo experiments in support of lead identification & optimization including PK-TE, PK-PD, and efficacy endpoints
- Run immune cell phenotypic and functional studies (surface marker expression, proliferation, cellular cytotoxicity, cytokine production) using multi-color flow cytometry, ELISA, Luminex, and qPCR
- Perform reporter cell line based in vitro screening assays
- Work closely and collaboratively with fellow scientists to develop and optimize in vivo models
- Analyze workflows and assay performance to increase efficiency and robustness of generated data
- Use common data analysis tools (Excel, Prism, FlowJo) and keep detailed documentation in an electronic lab notebook
- Collaborate closely with team members towards study design and planning; present results to the research team in weekly lab meetings
Qualifications and Skills
- B.S. or M.S. in relevant discipline with 3-7 years of industry experience, or PhD in relevant discipline with 1-3 years of industry experience
- Experience developing and executing rodent disease models (IACUC submission, study design and execution, data processing and presentation)
- Technically proficient with a track record in many aspects of in vivo rodent research (dosing routes, anesthesia, necropsy, tissue processing, etc.)
- Experience with multiple methods of tissue processing and analytical analysis (flow cytometry, ELISA, qPCR)
- Driven to both learn from, as well as teach, team members
- The ideal candidate is entrepreneurial, energetic, able to adapt to and shape a dynamic environment
- Eligible to work in the United States
Compensation
We offer a competitive salary, stock options, and health benefits. In addition, we provide a monthly activity stipend to cover a gym membership or other hobbies of interest.
Furthermore, we are a company that strongly believes in fostering the intellectual advancement of our team. As such, we support career development opportunities (online courses, seminars, conferences) that intersect with areas of interest for the company.
We value diversity of personal identity, experience, and thought. We will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, or disability status.
